Mestan Lab

Translational research in identifying biomarkers and mechanisms by which placental vascular dysfunction leads to neonatal lung disease and its long-term health sequelae

Research

Chronic lung diseases manifest differently in every infant. But why? The Mestan Lab is interested in identifying biochemical, environmental, and genetic markers that can lead to new therapies for predicting, preventing, and managing bronchopulmonary dysplasia and neonatal hypertension in high-risk infants.

After spending 20 years at Northwestern University researching disease in preterm infants and building a cord blood and placenta biorepository, Dr. Karen Mestan joined UC San Diego/Rady Children's Hospital as Division Chief of Neonatology in Fall 2021.

Latest Publications

Placental pathology and fetal growth outcomes in pregnancies complicated by maternal obesity

Samantha Hietalati, Donna Pham, Harneet Arora, Marina Mochizuki, Gisselle Santiago, Jordan Vaught, Erika T Lin, Karen K Mestan, Mana Parast, Marni B Jacobs

Int J Obes (Lond); 2024 Sep;48(9):1248-1257.

doi: 10.1038/s41366-024-01546-y.

PMID: 38822073