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Mestan Lab

Translational research in identifying biomarkers and mechanisms by which placental vascular dysfunction leads to neonatal lung disease and its long-term health sequelae

Image by Sharon McCutcheon

Research

Chronic lung diseases manifest differently in every infant. But why? The Mestan Lab is interested in identifying biochemical, environmental, and genetic markers that can lead to new therapies for predicting, preventing, and managing bronchopulmonary dysplasia and neonatal hypertension in high-risk infants. 

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After spending 20 years at Northwestern University researching disease in preterm infants and building a cord blood and placenta biorepository, Dr. Karen Mestan joined UC San Diego/Rady Children's Hospital as Division Chief of Neonatology in Fall 2021.

Latest Publications

Evolution of the umbilical cord blood proteome across gestational development

Leena B. Mithal, Nicola Lancki, Ted Ling-Hu, Young Ah Goo, Sebastian Otero, Nathaniel J. Rhodes, Byoung-Kyu Cho, William A. Grobman, Judd F. Hultquist, Denise Scholtens, Karen K. Mestan & Patrick C. Seed, Scientific Reports, 2025 Jan 17;15(1):2233​

DOI: 10.1038/s41598-024-84446-5.

PMID: 39825080

Image by Sharon McCutcheon

Our Location

Biomedical Research Facility II, Room 4220 Bay J at UC San Diego

3147 Biomedical Sciences Way

La Jolla, CA 92093

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